Some people with long COVID experience lingering symptoms such as fatigue, brain fog, anxiety, and muscle pain, which can significantly impact daily life. Hyperbaric Oxygen Therapy (HBOT) has emerged as a potential treatment by increasing oxygen levels in the bloodstream, reducing inflammation, and promoting healing. HBOT works by stimulating anti-inflammatory cytokines and growth factors, as well as boosting the expression of anti-inflammatory genes. Given the role of inflammation in long COVID, HBOT may offer relief for those experiencing persistent symptoms.